"The accelerated aging is not the same as precocious puberty (early signs of puberty before age 7 or 8 girls and 9 boys)," said Mieczyslaw Litwin, MD, Ph.D. , co-author of the study and scientific director at Childrens Memorial Health Institute in Warsaw, Poland. Accelerated ripening meant that the pace of biological maturity is greater than the average. We found that accelerated skeletal maturation may be the first telltale signs of developing hypertension."
To study the relationship between blood pressure and skeletal maturation, the researchers assessed the bone age in children and adolescents with hypertension compared to young healthy people matched for body mass index, age and sex.
Scientists X-ray of the left wrist of 54 hypertensive white Polish children and compared with X-ray images of 54 children with a white Polish optimal blood pressure. The two groups were compared with the images published in a reference atlas of skeletal development. The children were a 14-year average. Based on the Atlas of the rate of maturity were considered physiological, accelerated or delayed. In healthy subjects, the researchers found skeletal maturity in 20 cases against 48 cases in the hypertensive group.
The researchers also studied the relationship between hypertension and obesity, bone age. The results were remarkable, but no direct clinical application was declared. However, the researchers said that the accelerated bone maturation is only a sign of hormones and metabolic disorders. "It's hard to imagine that the process of maturation can be translated," said Litwin, who is also a professor at Tampere Nephrology and Hypertension Research Institute. "But we believe that some changes in lifestyle such as increased exercise and dietary changes can influence the metabolic disorders and the time of biological maturity."
Other co-authors are: Pawel Pludowski, Ph.D., Anna Niemirska, MD; Sladowski Juana, MD, Roman Lorenc, MD, Ph.D., Maciej Jaworski, Ph.D., Edyta Kryskiewicz, MSc. Karczmarewicz and Elzbieta, PhD Memorial Child Health Institute in Warsaw, Poland has financed the study.
Scientists X-ray of the left wrist of 54 hypertensive white Polish children and compared with X-ray images of 54 children with a white Polish optimal blood pressure. The two groups were compared with the images published in a reference atlas of skeletal development. The children were a 14-year average. Based on the Atlas of the rate of maturity were considered physiological, accelerated or delayed. In healthy subjects, the researchers found skeletal maturity in 20 cases against 48 cases in the hypertensive group.
The researchers also studied the relationship between hypertension and obesity, bone age. The results were remarkable, but no direct clinical application was declared. However, the researchers said that the accelerated bone maturation is only a sign of hormones and metabolic disorders. "It's hard to imagine that the process of maturation can be translated," said Litwin, who is also a professor at Tampere Nephrology and Hypertension Research Institute. "But we believe that some changes in lifestyle such as increased exercise and dietary changes can influence the metabolic disorders and the time of biological maturity."
Other co-authors are: Pawel Pludowski, Ph.D., Anna Niemirska, MD; Sladowski Juana, MD, Roman Lorenc, MD, Ph.D., Maciej Jaworski, Ph.D., Edyta Kryskiewicz, MSc. Karczmarewicz and Elzbieta, PhD Memorial Child Health Institute in Warsaw, Poland has financed the study.

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